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The effects of 4% niacinamide gel or cream in killing acne have been proven to be as effective as 1% clindamycin gel formulated products. The effects are even greater as niacinamide is not an antibiotic, it is an anti inflammatory and antibacterial substance that doesn’t act as an antigen which means the effects will be as effective as the first time use. The keratolytic property of niacinamide endowed in creams like Acnessential acne cream which is said to be one important use of it is that it sheds dead skin mildly that clogs pores and form as future blackheads. It is also said that this vitamin improves the reproduction of ceramide and moisture to the skin that keeps it from developing future fine lines and wrinkles.A lot of ingredients have disappointed dermatologists due to low efficacy in treating various skin problems. However, vitamin B3 has undergone clinical testing and established itself as being useful when applied topically.